1-(Chloromethyl)-3-(trifluoromethoxy)benzene, 3-(Chloromethyl)phenyl trifluoromethyl ether - Names and Identifiers
1-(Chloromethyl)-3-(trifluoromethoxy)benzene, 3-(Chloromethyl)phenyl trifluoromethyl ether - Physico-chemical Properties
Molecular Formula | C8H6ClF3O
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Molar Mass | 210.58 |
Density | 1.336±0.06 g/cm3(Predicted) |
Boling Point | 189.4±35.0 °C(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
1-(Chloromethyl)-3-(trifluoromethoxy)benzene, 3-(Chloromethyl)phenyl trifluoromethyl ether - Risk and Safety
Hazard Symbols | C - Corrosive
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1-(Chloromethyl)-3-(trifluoromethoxy)benzene, 3-(Chloromethyl)phenyl trifluoromethyl ether - Introduction
3-(Trifluoromethoxy)benzyl chloride is an organic compound with the chemical formula C8H6ClF3O. It is a colorless to slightly yellow liquid, volatile at room temperature. 3-(Trifluoromethoxy)benzyl chloride is highly corrosive. Care should be taken to avoid contact with skin and eyes, and protective gloves and glasses should be worn if necessary.
The 3-(Trifluoromethoxy)benzyl chloride can be used for a substitution reaction in organic synthesis, and is particularly suitable for linking a fluorine-containing functional group to a compound. It can be used as an intermediate for fluorinated reagents, such as for the synthesis of fluorinated drugs, pesticides, dyes and high-performance polymers. In addition, due to its ability as a protecting group in organic synthesis, it can also be used to study and synthesize organic compounds.
the method for preparing 3-(Trifluoromethoxy)benzyl chloride can use m-methoxyphenol to react with chloroform, and carry out chlorination reaction under alkaline conditions. The resulting 3-(Trifluoromethoxy)benzyl chloride can be purified by steam distillation.
When storing and using 3-(Trifluoromethoxy)benzyl chloride, you should pay attention to sealed storage and avoid contact with air and water. It should be stored in a cool, dry place, away from fire and flammable materials. During operation, good ventilation measures should be taken to avoid inhalation of vapors. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. Correct laboratory safety practices must be observed when handling the compound. Make sure you have sufficient expertise and experience when using the 3-(Trifluoromethoxy)benzyl chloride.
Last Update:2024-04-09 21:04:16